down 1.2%, down 3.4%, we have seen exxon and chevron coming under pressure. a downgrade for this particular group. the truth is overall the group is under pressure today and certainly underperforming when you look at the big picture. back to you. cheryl: thank you very much. it is the biggest health care event of the year. hundreds of companies, thousands of investors at the jpmorgan annual conference this week. showcase the latest against cancer. joining us the fox business exclusive is oliver, the ceo. thank you for being here. two big announcements from you any bavarian cancer, gastric cancer, but it is about nanotechnology. explain how that works. >> thank you very much. what we do is very simple in concept. why would you do that? you can target tumor tissue. tumors have blood vessels and you can make these small balls of the right size they fit through to the tumor and don't distribute to the rest of the body, so why would you do that, what is the point of doing that and packaging medicine that way? it gives you a preferential exposure in the tumor witho